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Population Frequence of Hg E & J and its subclades

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TheodoreFelix View Drop Down
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  Quote TheodoreFelix Quote  Post ReplyReply Direct Link To This Post Topic: Population Frequence of Hg E & J and its subclades
    Posted: 15-Jul-2005 at 23:33

 The phylogeography of Y-chromosome haplogroups E (Hg E) and J (Hg J) was investigated in >2,400 subjects from 29 populations, mainly from Europe and the Mediterranean area but also from Africa and Asia. The observed 501 Hg E and 445 Hg J samples were subtyped using 36 binary markers and eight microsatellite loci. Spatial patterns reveal that (1) the two sister clades, J-M267 and J-M172, are distributed differentially within the Near East, North Africa, and Europe; (2) J-M267 was spread by two temporally distinct migratory episodes, the most recent one probably associated with the diffusion of Arab people; (3) E-M81 is typical of Berbers, and its presence in Iberia and Sicily is due to recent gene flow from North Africa; (4) J-M172(xM12) distribution is consistent with a Levantine/Anatolian dispersal route to southeastern Europe and may reflect the spread of Anatolian farmers; and (5) E-M78 (for which microsatellite data suggest an eastern African origin) and, to a lesser extent, J-M12(M102) lineages would trace the subsequent diffusion of people from the southern Balkans to the west. A 7%22% contribution of Y chromosomes from Greece to southern Italy was estimated by admixture analysis.



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Maju View Drop Down
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  Quote Maju Quote  Post ReplyReply Direct Link To This Post Posted: 16-Jul-2005 at 04:19
That's interesting. Still the problem with Y-crhomosome and Mithocondrial DNA analysis is that they only show the direct patrilineal and matrilineal ancestor. So of my 4 grandparents only two are reflected in these kind of studies (1 for the Y chromosome and another for the Mt-DNA), of my 8 great-grandparents again only 2 are apparent, of my 16 great-grandparents still only 2 are reflected in these studies, etc. As you go far back in time the proportion of relevance becomes less and less significant.

One can imagine that, on random bases, eventually most of the ancient lineages would be anyhow reflected in a population through Y and Mt DNA but that's not necessarily true: any maternal lineage with only male offsprings is not reflected in Mt-DNA, if these male offsprings have (at some stage) only female ones, their genetic aportation is still relevant but their inheritance is not reflected in either Y chomosome or Mithocondrial DNA studies.

Still it will be reflected in wider studies that focus in all the genome, not just in strict patrilineal and matrilineal inherited genes. While it's curious to know about patrilineal and matrilineal ancestors... this may be almost irrelevant when it comes to study the true nature of the genetic pool of any population.

(Sidenote: recently some doubts have arised about Y chromosome not recombining... it may well be that Y, at least occasionally, recombines with X choromosome during fecundation)


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TheodoreFelix View Drop Down
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  Quote TheodoreFelix Quote  Post ReplyReply Direct Link To This Post Posted: 16-Jul-2005 at 12:12
Considering the fact that Im relatively new at this stuff, thanks for that explanation.
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