If we're talking 19th century, Johann Wolfgang von Goethe (1749-1832) came pretty close to be an "Uomo Universalis" or "renaissance man".
Although best known as a playwright, poet and novelist, he excelled also as a scientist, philosopher and diplomat.
I have no idea if he could paint or draw, he probably didn't have the time.
I can't think of any contempory person, for whom the label would fit, the specialisations of academic and artistic subjects have gone too far and too deep, but I will admire anybody who looks beyond his specific field, and instead of being what we call in German a "Fachidiot", looks at the bigger picture and sees his own subject in perspective and context.
Noam Chomsky does so, for example.
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